diff --git a/DEPS b/DEPS
index a1d0b0ba12..2c59464543 100644
--- a/DEPS
+++ b/DEPS
@@ -2619,30 +2619,6 @@ hooks = [
                 '-s', 'src/third_party/instrumented_libraries/binaries/msan-no-origins-focal.tgz.sha1',
               ],
   },
-  {
-    'name': 'msan_chained_origins_xenial',
-    'pattern': '.',
-    'condition': 'checkout_instrumented_libraries',
-    'action': [ 'python3',
-                'src/third_party/depot_tools/download_from_google_storage.py',
-                '--no_resume',
-                '--no_auth',
-                '--bucket', 'chromium-instrumented-libraries',
-                '-s', 'src/third_party/instrumented_libraries/binaries/msan-chained-origins-xenial.tgz.sha1',
-              ],
-  },
-  {
-    'name': 'msan_no_origins_xenial',
-    'pattern': '.',
-    'condition': 'checkout_instrumented_libraries',
-    'action': [ 'python3',
-                'src/third_party/depot_tools/download_from_google_storage.py',
-                '--no_resume',
-                '--no_auth',
-                '--bucket', 'chromium-instrumented-libraries',
-                '-s', 'src/third_party/instrumented_libraries/binaries/msan-no-origins-xenial.tgz.sha1',
-              ],
-  },
   {
     # Download test resources, i.e. video and audio files from Google Storage.
     'pattern': '.',