diff --git a/rtc_base/critical_section.cc b/rtc_base/critical_section.cc
index 4a5c53b54d..9e3615ee0c 100644
--- a/rtc_base/critical_section.cc
+++ b/rtc_base/critical_section.cc
@@ -31,7 +31,7 @@ CriticalSection::CriticalSection() {
 #if defined(WEBRTC_WIN)
   InitializeCriticalSection(&crit_);
 #elif defined(WEBRTC_POSIX)
-#if defined(WEBRTC_MAC) && !USE_NATIVE_MUTEX_ON_MAC
+#if defined(WEBRTC_MAC) && !RTC_USE_NATIVE_MUTEX_ON_MAC
   lock_queue_ = 0;
   owning_thread_ = 0;
   recursion_ = 0;
@@ -60,7 +60,7 @@ CriticalSection::~CriticalSection() {
 #if defined(WEBRTC_WIN)
   DeleteCriticalSection(&crit_);
 #elif defined(WEBRTC_POSIX)
-#if defined(WEBRTC_MAC) && !USE_NATIVE_MUTEX_ON_MAC
+#if defined(WEBRTC_MAC) && !RTC_USE_NATIVE_MUTEX_ON_MAC
   dispatch_release(semaphore_);
 #else
   pthread_mutex_destroy(&mutex_);
@@ -74,7 +74,7 @@ void CriticalSection::Enter() const RTC_EXCLUSIVE_LOCK_FUNCTION() {
 #if defined(WEBRTC_WIN)
   EnterCriticalSection(&crit_);
 #elif defined(WEBRTC_POSIX)
-#if defined(WEBRTC_MAC) && !USE_NATIVE_MUTEX_ON_MAC
+#if defined(WEBRTC_MAC) && !RTC_USE_NATIVE_MUTEX_ON_MAC
   int spin = 3000;
   PlatformThreadRef self = CurrentThreadRef();
   bool have_lock = false;
@@ -133,7 +133,7 @@ bool CriticalSection::TryEnter() const RTC_EXCLUSIVE_TRYLOCK_FUNCTION(true) {
 #if defined(WEBRTC_WIN)
   return TryEnterCriticalSection(&crit_) != FALSE;
 #elif defined(WEBRTC_POSIX)
-#if defined(WEBRTC_MAC) && !USE_NATIVE_MUTEX_ON_MAC
+#if defined(WEBRTC_MAC) && !RTC_USE_NATIVE_MUTEX_ON_MAC
   if (!IsThreadRefEqual(owning_thread_, CurrentThreadRef())) {
     if (AtomicOps::CompareAndSwap(&lock_queue_, 0, 1) != 0)
       return false;
@@ -173,7 +173,7 @@ void CriticalSection::Leave() const RTC_UNLOCK_FUNCTION() {
   if (!recursion_count_)
     thread_ = 0;
 #endif
-#if defined(WEBRTC_MAC) && !USE_NATIVE_MUTEX_ON_MAC
+#if defined(WEBRTC_MAC) && !RTC_USE_NATIVE_MUTEX_ON_MAC
   RTC_DCHECK(IsThreadRefEqual(owning_thread_, CurrentThreadRef()));
   RTC_DCHECK_GE(recursion_, 0);
   --recursion_;
@@ -217,14 +217,15 @@ CritScope::~CritScope() {
 }
 
 void GlobalLockPod::Lock() {
-#if !defined(WEBRTC_WIN) && (!defined(WEBRTC_MAC) || USE_NATIVE_MUTEX_ON_MAC)
+#if !defined(WEBRTC_WIN) && \
+    (!defined(WEBRTC_MAC) || RTC_USE_NATIVE_MUTEX_ON_MAC)
   const struct timespec ts_null = {0};
 #endif
 
   while (AtomicOps::CompareAndSwap(&lock_acquired, 0, 1)) {
 #if defined(WEBRTC_WIN)
     ::Sleep(0);
-#elif defined(WEBRTC_MAC) && !USE_NATIVE_MUTEX_ON_MAC
+#elif defined(WEBRTC_MAC) && !RTC_USE_NATIVE_MUTEX_ON_MAC
     sched_yield();
 #else
     nanosleep(&ts_null, nullptr);
diff --git a/rtc_base/critical_section.h b/rtc_base/critical_section.h
index 4433529886..f9047a6b07 100644
--- a/rtc_base/critical_section.h
+++ b/rtc_base/critical_section.h
@@ -34,9 +34,9 @@
 #endif
 
 // See notes in the 'Performance' unit test for the effects of this flag.
-#define USE_NATIVE_MUTEX_ON_MAC 1
+#define RTC_USE_NATIVE_MUTEX_ON_MAC 1
 
-#if defined(WEBRTC_MAC) && !USE_NATIVE_MUTEX_ON_MAC
+#if defined(WEBRTC_MAC) && !RTC_USE_NATIVE_MUTEX_ON_MAC
 #include <dispatch/dispatch.h>
 #endif
 
@@ -61,7 +61,7 @@ class RTC_LOCKABLE CriticalSection {
 #if defined(WEBRTC_WIN)
   mutable CRITICAL_SECTION crit_;
 #elif defined(WEBRTC_POSIX)
-#if defined(WEBRTC_MAC) && !USE_NATIVE_MUTEX_ON_MAC
+#if defined(WEBRTC_MAC) && !RTC_USE_NATIVE_MUTEX_ON_MAC
   // Number of times the lock has been locked + number of threads waiting.
   // TODO(tommi): We could use this number and subtract the recursion count
   // to find places where we have multiple threads contending on the same lock.