diff --git a/modules/rtp_rtcp/source/rtp_sender.cc b/modules/rtp_rtcp/source/rtp_sender.cc
index 6989efca5d..1c3cb286dd 100644
--- a/modules/rtp_rtcp/source/rtp_sender.cc
+++ b/modules/rtp_rtcp/source/rtp_sender.cc
@@ -155,12 +155,6 @@ double GetMaxPaddingSizeFactor(const FieldTrialsView* field_trials) {
 
 }  // namespace
 
-RTPSender::RTPSender(const RtpRtcpInterface::Configuration& config,
-                     RtpPacketHistory* packet_history,
-                     RtpPacketSender* packet_sender,
-                     PacketSequencer*)
-    : RTPSender(config, packet_history, packet_sender) {}
-
 RTPSender::RTPSender(const RtpRtcpInterface::Configuration& config,
                      RtpPacketHistory* packet_history,
                      RtpPacketSender* packet_sender)
diff --git a/modules/rtp_rtcp/source/rtp_sender.h b/modules/rtp_rtcp/source/rtp_sender.h
index 0a80836624..cb2c99e122 100644
--- a/modules/rtp_rtcp/source/rtp_sender.h
+++ b/modules/rtp_rtcp/source/rtp_sender.h
@@ -26,7 +26,6 @@
 #include "modules/rtp_rtcp/include/rtp_header_extension_map.h"
 #include "modules/rtp_rtcp/include/rtp_packet_sender.h"
 #include "modules/rtp_rtcp/include/rtp_rtcp_defines.h"
-#include "modules/rtp_rtcp/source/packet_sequencer.h"
 #include "modules/rtp_rtcp/source/rtp_packet_history.h"
 #include "modules/rtp_rtcp/source/rtp_rtcp_config.h"
 #include "modules/rtp_rtcp/source/rtp_rtcp_interface.h"
@@ -47,14 +46,6 @@ class RTPSender {
   RTPSender(const RtpRtcpInterface::Configuration& config,
             RtpPacketHistory* packet_history,
             RtpPacketSender* packet_sender);
-
-  ABSL_DEPRECATED("bugs.webrtc.org/11340")
-  RTPSender(const RtpRtcpInterface::Configuration& config,
-            RtpPacketHistory* packet_history,
-            RtpPacketSender* packet_sender,
-            PacketSequencer* packet_sequencer);
-
-  RTPSender() = delete;
   RTPSender(const RTPSender&) = delete;
   RTPSender& operator=(const RTPSender&) = delete;
 
diff --git a/modules/rtp_rtcp/source/rtp_sender_unittest.cc b/modules/rtp_rtcp/source/rtp_sender_unittest.cc
index c28dd684db..6eba47741c 100644
--- a/modules/rtp_rtcp/source/rtp_sender_unittest.cc
+++ b/modules/rtp_rtcp/source/rtp_sender_unittest.cc
@@ -170,7 +170,7 @@ class RtpSenderTest : public ::testing::Test {
                        /*require_marker_before_media_padding=*/!config.audio,
                        clock_);
     rtp_sender_ = std::make_unique<RTPSender>(config, packet_history_.get(),
-                                              config.paced_sender, nullptr);
+                                              config.paced_sender);
     sequencer_->set_media_sequence_number(kSeqNum);
     rtp_sender_->SetTimestampOffset(0);
   }