diff --git a/modules/rtp_rtcp/BUILD.gn b/modules/rtp_rtcp/BUILD.gn
index 0ac6900e65..c9a3161111 100644
--- a/modules/rtp_rtcp/BUILD.gn
+++ b/modules/rtp_rtcp/BUILD.gn
@@ -463,6 +463,7 @@ if (rtc_include_tests) {
       "source/rtcp_sender_unittest.cc",
       "source/rtcp_transceiver_impl_unittest.cc",
       "source/rtcp_transceiver_unittest.cc",
+      "source/rtp_dependency_descriptor_extension_unittest.cc",
       "source/rtp_fec_unittest.cc",
       "source/rtp_format_h264_unittest.cc",
       "source/rtp_format_unittest.cc",
diff --git a/modules/rtp_rtcp/source/rtp_dependency_descriptor_extension_unittest.cc b/modules/rtp_rtcp/source/rtp_dependency_descriptor_extension_unittest.cc
new file mode 100644
index 0000000000..244bef8579
--- /dev/null
+++ b/modules/rtp_rtcp/source/rtp_dependency_descriptor_extension_unittest.cc
@@ -0,0 +1,73 @@
+/*
+ *  Copyright (c) 2020 The WebRTC project authors. All Rights Reserved.
+ *
+ *  Use of this source code is governed by a BSD-style license
+ *  that can be found in the LICENSE file in the root of the source
+ *  tree. An additional intellectual property rights grant can be found
+ *  in the file PATENTS.  All contributing project authors may
+ *  be found in the AUTHORS file in the root of the source tree.
+ */
+
+#include "modules/rtp_rtcp/source/rtp_dependency_descriptor_extension.h"
+
+#include "api/array_view.h"
+#include "api/transport/rtp/dependency_descriptor.h"
+#include "common_video/generic_frame_descriptor/generic_frame_info.h"
+
+#include "test/gmock.h"
+
+namespace webrtc {
+namespace {
+
+using ::testing::Each;
+
+TEST(RtpDependencyDescriptorExtensionTest, Writer3BytesForPerfectTemplate) {
+  uint8_t buffer[3];
+  FrameDependencyStructure structure;
+  structure.num_decode_targets = 2;
+  structure.num_chains = 2;
+  structure.templates = {GenericFrameInfo::Builder()
+                             .Dtis("SR")
+                             .Fdiffs({1})
+                             .ChainDiffs({2, 2})
+                             .Build()};
+  DependencyDescriptor descriptor;
+  descriptor.frame_dependencies = structure.templates[0];
+
+  EXPECT_EQ(RtpDependencyDescriptorExtension::ValueSize(structure, descriptor),
+            3u);
+  EXPECT_TRUE(
+      RtpDependencyDescriptorExtension::Write(buffer, structure, descriptor));
+}
+
+TEST(RtpDependencyDescriptorExtensionTest, WriteZeroInUnusedBits) {
+  uint8_t buffer[32];
+  std::memset(buffer, 0xff, sizeof(buffer));
+  FrameDependencyStructure structure;
+  structure.num_decode_targets = 2;
+  structure.num_chains = 2;
+  structure.templates = {GenericFrameInfo::Builder()
+                             .Dtis("SR")
+                             .Fdiffs({1})
+                             .ChainDiffs({1, 1})
+                             .Build()};
+  DependencyDescriptor descriptor;
+  descriptor.frame_dependencies = structure.templates[0];
+  descriptor.frame_dependencies.frame_diffs = {2};
+
+  // To test unused bytes are zeroed, need a buffer large enough.
+  size_t value_size =
+      RtpDependencyDescriptorExtension::ValueSize(structure, descriptor);
+  ASSERT_LT(value_size, sizeof(buffer));
+
+  ASSERT_TRUE(
+      RtpDependencyDescriptorExtension::Write(buffer, structure, descriptor));
+
+  const uint8_t* unused_bytes = buffer + value_size;
+  size_t num_unused_bytes = buffer + sizeof(buffer) - unused_bytes;
+  // Check remaining bytes are zeroed.
+  EXPECT_THAT(rtc::MakeArrayView(unused_bytes, num_unused_bytes), Each(0));
+}
+
+}  // namespace
+}  // namespace webrtc
diff --git a/modules/rtp_rtcp/source/rtp_dependency_descriptor_writer.cc b/modules/rtp_rtcp/source/rtp_dependency_descriptor_writer.cc
index d933a94128..df5310b6ba 100644
--- a/modules/rtp_rtcp/source/rtp_dependency_descriptor_writer.cc
+++ b/modules/rtp_rtcp/source/rtp_dependency_descriptor_writer.cc
@@ -75,9 +75,12 @@ bool RtpDependencyDescriptorWriter::Write() {
     WriteFrameDependencyDefinition();
   }
   size_t remaining_bits = bit_writer_.RemainingBitCount();
-  if (remaining_bits > 0) {
-    // Zero remaining memory to avoid leaving it uninitialized.
-    WriteBits(/*val=*/0, remaining_bits);
+  // Zero remaining memory to avoid leaving it uninitialized.
+  if (remaining_bits % 64 != 0) {
+    WriteBits(/*val=*/0, remaining_bits % 64);
+  }
+  for (size_t i = 0; i < remaining_bits / 64; ++i) {
+    WriteBits(/*val=*/0, 64);
   }
   return !build_failed_;
 }